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Similarly, oil red O staining of aortic root cross-sections showed a significantly decreased oil red O-positive staining area in the HCD + ALC group compared with that of the HCD group (Figures 5B,C)

Also, chronic brain inflammation could elevate systemic inflammation levels, leading to further organ damage

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Thus, as we have more knowledge of the risk from the exposure to environmental pollutants, more well-designed epidemiological studies (controlling for as many variables as possible and with high sample sizes) are necessary to improve the quality of life of elderly and to prevent the development of neurodegenerative diseases worldwide

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