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Conversely, since the LDH isoform derived from the LDHB gene is primarily responsible for the oxidation of lactate to pyruvate the high level of LDHB expression in -cells ensures that the bulk of lactate generated from pyruvate via the actions of LDHA derived LDH is rapidly oxidized back to pyruvate

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doi: 10.1016/j.rbmo.2020.10.003 87 CalzadaMLpezNNogueraJAMendiolaJHernndezAICorbalnSet al

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