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It is important to highlight that CSF2 and CXCL10 encode pro-inflammatory proteins linked to neurodegenerative diseases 51,52,53 , and, as mentioned above, elevated levels of CXCL10 protein are associated with persistent VCD in individuals from the same cohort of the present study 20

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For patients on newer antidepressants, which are more common (e.g., Prozac, Paxil, Zoloft, Celexa, Effexor), we are unaware of any adverse interactions