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Geographical distribution of folate-mediated one-carbon metabolism pathway alleles and genotypes showing continental differences but not major intra-population differences in Mexican Mestizos Four of the eight variants analyzed, FOLH1 T484C, TCN2 C77G, SLC19A1 A80G and MTR A2756G, showed a similar average frequency distribution between MEX, AMI and EUR groups (MAF frequencies: 2326, 3143, 5458 and 1725 %, respectively), which correlates with either no significant differences or very low variation in their frequency within MEX groups (Figs

for all globins discussed, there is compelling evidence that NO homeostasis is highly regulated by this family of hemoproteins

has received research funding and consulting honoraria from AbbVie, Adaptive Biotechnology, Amgen, Celgene/Bristol Myers Squibb, GSK, Janssen, Novartis, Oncopeptide, Regeneron, Roche, and Takeda

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