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Further pharmacological investigations and clinical trials are warranted to validate their efficacy as monotherapy or adjunctive treatments in pediatric neuropsychiatric disorders, particularly in patients sensitive to adverse drug reactions or requiring long-term management

In LPS-activated M1 macrophages, lactate-derived lactylation initiates a unique genetic program that blurs the line between classical polarization states, driving the expression of both pro-inflammatory and homeostatic genes [15]

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Cortisone provides rapid anti-inflammatory relief and can break pain cycles

Glutathione synthesis, transport and metabolism in Lactobacillus genus have been studied for some species but most are yet to be explored