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PainType Specific Mechanisms 3.2.1

Polyphenols have been shown to enhance tight junction integrity, increase mucus secretion, and decrease intestinal barrier permeability, thereby generally improving the intestinal defense mechanism [156,160]

doi: 10.1101/gr.1239303 [DOI] [PMC free article] [PubMed] [Google Scholar] 39

Studies have demonstrated that NAD administration can rescue cognitive deficits and inhibit neuroinflammation by protecting mitochondria and decreasing reactive oxygen species production

Biochem Biophys Res Commun 497:207213

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