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Therefore, unlike with reduced folates where intestinal absorption is followed by direct incorporation into the liver, some of the UMFA in the portal blood likely bypasses the liver to subsequently bind to folate receptors on peripheral tissues such as the kidney (58)

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Vegetarian : periodic B12 test maintenance dose (tablet/syrup) diet + supplement Q5

Some medications can reduce the ability to absorb vitamin b12, such as proton pump inhibitors, and PPIs