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The aim of this study was to evaluate the effects of CD8 antibodies modified PD-1 engineered CD8+ T lymphocytes (CTL) membrane loaded poly lactic-co-glycolic acid (PLGA)/ferroptosis inhibitor ferrostatin-1 (Fer-1) (CD8@PD-1-CTL-M@PLGA/Fer-1) on acute lung injury (ALI)