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Cu 2+ complexes of bis-thiosemicarbazones, especially Cu(gtsm), have been demonstrated to increase intracellular copper levels and decrease secreted A levels in APP-CHO cells

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Airway epithelial cells cocultured with eosinophils increased MUC5AC secretion directly in an amphiregulin- and TGF--dependent mechanism (Shimizu et al., 2014)

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