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Long-term exposure to neonicotinoid insecticide Acetamiprid at environmentally relevant concentrations impairs endocrine functions in Zebrafish: bioaccumulation, feminization, and transgenerational effects

Morphologically, light and electron microscopic examinations of irradiated testes have revealed marked disorganization, desquamation, and vacuolization of the germ cells of rats seminiferous tubules, as well as formation of multinucleated giant cells in the germinal epithelium following spermatogenesis arrest, compared to the unirradiated testes

De Clercq, 2007)

A double-blinded, crossover study

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