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Combination of RUNX1 inhibitor and gemcitabine mitigates chemo-resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2-axis-mediated endoplasmic reticulum stress
10.1002/fsn3.4312 Contributor Information Muzzamal Hussain, Email: [email protected]

Traditional diagnostic methods often rely on subjective assessments and limited laboratory results, which can lead to misdiagnosis and, thus, delayed treatment

Dr Emma Dempster, Senior Lecturer at the University of Exeter and the studys first author Dr Emma Dempster meta-analysed data from two cohorts: the GAP study, which consists of patients with first episode psychosis in South London and Maudsley NHS Foundation Trust, and the EU-GEI study, which consists of patients with first-episode psychosis and healthy controls across England, France, the Netherlands, Italy, Spain and Brazil

Protecting cells from oxidative damage: It safeguards cellular structures such as DNA, proteins, and membranes from damage caused by oxidative stress (NIH)

Trafficking to tumor sites is another main challenge faced by BiTEs and CAR-T cells