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This has been considered the arginine paradox. Several mechanisms have been proposed to explain this phenomenon

Donadeu FX, Schauer SN, Sontakke SD

doi: 10.2147/CCID.S457958

Adv Sci (Weinheim Baden-Wurttemberg Ger

Induction of mitochondria-involved apoptosis in estrogen receptor-negative cells by a novel tamoxifen derivative, ridaifen-B
