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A high-affinity, saturable transport mechanism for DSIP at the blood-brain barrier was demonstrated in vascularly perfused guinea pig brain, with the highest unidirectional transfer rate in the hippocampus (Kin 1.66 L/min/g) [9]

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Mao EJ, Hazlewood GS, Kaplan GG et al (2017) Systematic review with meta-analysis: comparative efficacy of immunosuppressants and biologics for reducing hospitalisation and surgery in Crohns disease and ulcerative colitis

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