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Figure 3 Phytic Acid Phytic acid is a natural antioxidant found naturally in the form of salts and is present in cereals, vegetables, nuts, and natural oils ( Early studies showed that phytic acid is considered an antinutritional component because of its ability to chelate with minerals, but recent studies proposed that phytic acid performs well in various pathological conditions, intoxication, and cancer ( Low-phytate pea affects iron bioavailability, physiological status, gut microbiota composition and metagenome, and intestinal function ( Non-Starch Polysaccharides Non-starch polysaccharides, together with resistant starch and lignin from the dietary fiber, are found in plants especially in the endospermic cell wall of multiple kinds of seeds ( In the past, NSPs are considered an antinutritional factor because they increase the viscosity of digests and inhibit digestion

Furthermore, IR increases hepatic De novo lipogenesis (DNL) and stimulates adipose tissue to secrete adipokine and inflammatory cytokine, ultimately leading to the dysregulation of adipose tissues lipolytic processes [26]

Because the level of acetaminophen at the time of the predetoxification assay may not be a peak value (peak may not be achieved before 4 hours post-ingestion), obtain a second plasma level in order to decide whether or not the full 17-dose detoxification treatment is necessary