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10.3390/biomedicines9070792 42 KolovratM.GojkovicS.KrezicI.MalekinusicD.VrdoljakB.Kasnik KovacK.et al (2020)

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However, combination-specific human clinical evidence remains limited, and most available data comes from laboratory and animal studies

Yadav S, Gattacceca F, Panicucci R, Amiji MM

For instance, mephedrone increases both dopamine and serotonin release, whereas -PVP primarily targets dopamine and norepinephrine transporters ( 4.2 Oxidative stress and mitochondrial dysfunction The excessive release of monoamines promotes ROS formation through the auto-oxidation of dopamine and norepinephrine
