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T-cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

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Mice treated with antibiotics or reared germ free are resistant to KD-mediated seizure protection, whereas enrichment of Akkermansia muciniphila and Parabacteroides populations restores anti-epileptic effect of KD (76)

The role of dopamine in psoriasis pathogenesis is further supported by multiple case studies reporting the worsening of psoriasis in patients treated with the atypical antipsychotic olanzapine, which acts as a high-affinity antagonist at both dopamine and serotonin receptors (Ascari-Raccagni et al., 2000