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In this context, we found, that treatment of the differentiated mouse hippocampal HT-22 neurons with STW3-VI supported/enhanced the growth of neurites compared to neurons incubated with medium alone (control), suggesting that these neurotrophic properties might play a role in its positive effects on depression in vivo

Cell division cycle 48 (Cdc48) enhances the activity of the HSC70-Hsp40 complex
Overall, exposure to escitalopram/citalopram results in shifts in metabolism through noncanonical pathways, which suggest possible roles for the gut microbiome, oxidative stress, and inflammation-related mechanisms
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