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Oxidative stress, and both apoptotic and necrotic phenomena may be enhanced
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[56], the inhibition of NF-B, in whose regulation zinc plays a critical role, holds up the expression of NOX1 and NOX4, which play an important role in redox status determination in blood vessels

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A systematic review of toxicity, biodistribution, and biosafety in upconversion nanomaterials: critical insights into toxicity mitigation strategies and future directions for safe applications
