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Tsou HH, Hsu WC, Fuh JL, Chen SP, Liu TY, and Wang HT

One gene coding for glutaredoxin (PFC0271c) and two genes coding for glutaredoxin-like proteins (the exact function is unknown) have been found in the genome of P

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ROS detoxification via enzymes Superoxide dismutase The catalysts for the disproportionation of superoxide ions to hydrogen peroxide in S

Furthermore, a deficiency in Zip7 shifts macrophage activation towards an M2 phenotype, as evidenced by increased expression of the M2 marker CD206 and reduced levels of the M1 marker NOS2, along with lower production of proinflammatory cytokines such as TNF- and IL-6