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These anaerobes produce metabolites, including short-chain fatty acids, polyamines, ammonia, and volatile amines, that can irritate the epithelium, damage DNA, and cause oxidative stress

doi: 10.1016/j.jpba.2006.11.028
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Muhoberac BB, Baraibar MA, Vidal R

Kanaoka Y, Fujimori K, Kikuno R, Sakaguchi Y, Urade Y, Hayaishi O (2000) Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase
