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Gut microbiota changes in metabolic dysfunction-associated steatohepatitis and inflammatory bowel disease: Common pathogenic features

Ceruloplasmin, an abundant acute phase protein in plasma, acts as an important antioxidant, which has been shown to directly bind and inhibit MPO [322], interfere with HOCl production [323] and thus, for instance, prevent HOCl-mediated degradation of the 1 -antiproteinase and other proteins [30]

Int Immunopharmacol 116:109754 Sies H (2015) Oxidative stress: a concept in redox biology and medicine

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We then inspected the PanDDA events (Fig