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This cascade directly promotes lipid peroxidation and ferroptosis (40, 67, 69) ( Figure 2 )

We confirmed this for ML162 and RSL3 but found that ESA or the negative control erastin had no effect on GPX4 levels (Fig

Increased intracellular calcium inhibits enzymes responsible for the distribution of phospholipids in plasma membranes and the release of cytochrome C and apoptosis-inducing factors, triggering neuronal apoptotic death, suppressing neurotransmission, and cognitive dysfunction (Bezprozvanny and Mattson 2018)

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Mei X, Gu M, Li M

Therefore, we evaluated alterations in immune cell infiltration in the lungs of LPS-administered mice with or without GHK-Cu pretreatment