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202,234,235 During the dormant phase, these metastasis-initiating progenitors are in equilibrium between an immune-privileged quiescent state and a proliferative state liable to immune-mediated clearance (Figure 6)

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Preclinical findings consistently support BPC-157 for tendon and ligament recovery across multiple injury models

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However, as cuproptosis may also increase ROS levels, excessive lipid peroxidation can trigger inflammation that might recruit additional immunosuppressive cells, posing challenges to the therapeutic potential [87]

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TABLE 3 Engineered EVs as drug delivery vehicles to treat IBD and CRC

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Molecular and cellular endocrinology 460 , 7384, (2018)

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