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Recent population-scale genomic analysis demonstrated that protein-truncating variants in mitochondrial-related nuclear genes markedly increase the risks of hepatic fibrosis, cirrhosis, and related mortality, underscoring mitochondrial dysfunction as a causal determinant of chronic liver disease [119]

All reconstitution solution products are stored under Controlled Room Temperature (CRT) conditions prior to shipment

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The RT-qPCR primers are listed in Table 1

Although the proportion of PD patients harboring pathogenic genetic variants is significant, with estimates ranging from 5%15% to over 40% (Lim et al., 2024), most cases are sporadic

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