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In addition to enzymatic degradation, chemical methods have been used both to modify the structure of mucus for drug delivery and to treat mucus overproduction

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[Google Scholar] Hopkins F.G., Morgan E.J

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Although epigenetic disorders can be transmitted via sperm [6,60,63], ROS may also affect the primary sperm DNA structure directly via the formation of DNA adducts such as 8-oxo deoxyguanosine: all of the nuclear bases may be affected by oxidation, but guanine is the most sensitive