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Other case studies and open-label studies, albeit without the necessary experimental controls, also reported significant improvements in behavioral assessments using ADOS-2, a social responsiveness scale (SRS), and vineland adaptive behavior scales (VABSs) [79], in addition to enhancements of focusing and learning capabilities [80]

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The cholinergic anti-inflammatory pathway, mediated by acetylcholine release via the vagus nerve, is another potential therapeutic target[84]

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