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PMID: 177 RigatoC.BuckinxR.Le-CorroncH.RigoJ

The tumor suppressor protein p53 increases the expression of the aspartate/glutamate transporter SLC1A3 and the arginine transporter SLC7A3 upon glutamine depletion, leading to resistance to treatments that deplete extracellular glutamine 114,115

A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation

CoQ10 has a favorable safety and tolerability profile at recommended dosages (typically around 100 mg/day), with studies indicating no significant adverse effects even following prolonged exposure to doses as high as 900 mg/day (171)

Asian J Andrology

The VEGFA gene plays a crucial role in angiogenesis, with polymorphisms such as rs699947, rs833061, and rs2010963 significantly affecting the extent of retinal neovascularization, a primary driver of PDR