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For each eligible study, two authors (MM and AN) independently extracted data, which was then reviewed by a third author (JV) using a piloted spreadsheet, in accordance with Cochrane Collaboration guidelines ( Where relevant data were missing, attempts were made to contact corresponding authors

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However, the effectiveness of B12 injections may vary from person to person

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Conditions such as pernicious anemia, which affects the absorption of B12, may also warrant coverage, as well as certain chemotherapy treatments that necessitate B12 supplementation