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Because these peptides act through distinct biological mechanisms, researchers frequently investigate them together to explore potential synergistic effects

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Shared neoantigens with high immunogenicity have the potential to be used as broad-spectrum therapeutic cancer vaccines for patients with the same mutant gene (Klebanoff and Wolchok, 2018

[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Quyen D.T., Irei A.V., Sato Y., Ota F., Fujimaki Y., Sakai T., Kunii D., Khan N.C., Yamamoto S

Researchers may use this solution in laboratory settings requiring accurate small-volume preparation and regulated sterile handling conditions

Third, as we will detail below (see Potential Pathogenic Mechanisms of Hyperhomocysteinemia), our own work (Durand et al, 1997a) and the work of Lentz et al (1996) and Bellamy et al (1998) give experimental evidence that moderate hyperhomocysteinemia, which leads to vascular dysfunction, might increase the cardiovascular risk independently of other risk factors