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Neuron 52 : 255269
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ROS and melanogenesis Melanogenesis is an oxygen-dependent process, which consists of a sequence of oxidation reactions accompanied by the generation of O 2 and H 2 O 2
Additionally, G4 carries intrinsic antimicrobial activity due to its strongly positive surface charge, supporting its potential use against CRKP (Han et al., 2023
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This has made MOTS-c a recurring reference point in comparative studies examining mitochondrial signaling alongside more traditional hormone-pathway peptides
