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The peptide significantly increases brain-derived neurotrophic factor expression, particularly in the hippocampus and prefrontal cortex, regions critical for memory formation and executive function

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Kozyraki, R., Fyfe, J., Kristiansen, M., Gerdes, C., Jacobsen, C., Cui, S., Krahe, R

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In summary, only three of the eleven patients with confirmed B 12 deficiency had hematologic data to corroborate clinical deficiency

Because there is no study confirming or excluding milk-compartment transfer of those nanoparticles, the conservative recommendation across lactation medicine is to defer