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Not all drugs need to reach the systemic circulation to exert their effects, for example, oral vancomycin used to treat pseudomembranous colitis

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Role of c-Met in drug resistance A variety of preclinical data have demonstrated that amplification of c-Met signaling occurs in many malignancies as a result of MET gene mutation or overexpression

Fast-forward 400 years, and some of the wealthiest individuals and companies are bankrolling antiaging research as the glacial, careful pace of science doesnt necessarily fit Silicon Valleys move-fast-and-break-things ethos

Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome

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