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Taylor et al , 2021) Analysis of two of these genes, mec2 (expressed in mechanosensory neurons) and unc24 (wide neuronal expression), showed that only unc24 mutants have a phenotype comparable to unc1 mutants, suggesting that not all neuronal stomatinlike proteins are involved in the regulation of polyQ aggregation (Appendix Table S3)

Galloway, S

The angiopoietin-like protein angptl4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein gpihbp1 counteracts this unfolding

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Therefore, it is possible that the expression of hsp-4p::gfp reporter is compromised in hsf-1 (RNAi) animals because decreased HSP-70 and/or HSP-90 protein levels result in IRE-1 destabilization

1978 A Study of Settlement Patterns of Southern Nevada as Reflected by the Archaeological Record