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System Xc(-): a key regulatory target of ferroptosis in cancer

de Ftima Dos Santos Sampaio M, de Paiva YB, Sampaio TB, Pereira MG, Coimbra NC

Previous studies have demonstrated that hydrogen gas can inhibit the formation of nitrotyrosine (Zhang et al., 2016), a detectable marker for the indirect measurement of ONOO (Wu et al., 2018), suggesting that hydrogen gas may exert its antioxidant effects by inhibiting ONOO

418 An intravenous preparation of Chinese ginseng saponins has also been widely studied for its ability to prevent and treat venous thrombosis, similar to Western clot busters. A meta-analysis of 20 randomized controlled trials with a total of 2,336 participants who had undergone orthopedic surgery due to fracture found those given injections containing ginseng saponins had fewer DVTs, lower D-dimer levels, and longer prothrombin and thrombin times

Zumbrennen-Bullough KB, Becker L, Garrett L, Holter SM, Calzada-Wack J, Mossbrugger I et al (2014) Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments