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The potential effects of microplastics on human health: what is known and what is unknown

Oral pycnogenol 50 mg twice daily has been suggested to treat melasma, reducing 58% of MASI in 31 Brazilian women after 90 days [87]

Intracellular GSSG levels were low and did not differ between the groups (overall P = 0.440)

However, the application is limited by the scarcity of donor tissue, additional trauma to the patient and surgical complications ( The complexity of the bone defect microenvironment makes cells vulnerable to various factors during regeneration and repair, creating substantial challenges for bone healing and clinical implementation of bone tissue engineering

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doi: 10.1146/annurev.arplant.51.1.141