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These compounds exhibit antioxidant activities thereby protecting the neurons from oxidative stress, inhibit apoptosis, and reduce inflammation thus preventing neurodegenerative diseases (86)
Furthermore, SNPs can inhibit malignant cells spread by reducing angiogenesis within the lesion or inducing malignant cell apoptosis by deactivating proteins and controlling signaling pathways
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NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model
