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This is primarily due to changes in digestive function and stomach acid production

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Plasma and serum vitamin B12 levels have been found to be essentially the same (Sviland, 1985)

do not increase the dosage without professional guidance

Commercial oral supplements likely deliver negligible active peptide despite marketing claims

Both recommend early treatment of acute localized LD because over 80% of patients treated for early LD have long-term complete resolution of symptoms