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Decreased NO and increased oxidative stress (OS) impairs endothelial [34,35] and macrophage function [36] and increases inflammatory cytokines, such as tumor necrosis factor (TNF) and monocyte chemoattractant protein-1 (MCP-1) in endothelial cells and monocytes [34,35]

According to MedicineNet, if Althea pills are not used solely for birth control purposes, one should practice caution while using them

Regular monitoring and patient education about potential side effects are essential components of successful treatment

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However, stacking increases complexity and potential risk especially if done without medical guidance