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Am J Clin Nutr 1994;59(5 Suppl):1213S-22S

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When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations

Genotoxicity testing, which evaluates whether a compound can damage DNA, found no evidence that 5-amino-1mq causes genetic damage