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This helps resolve symptoms of deficiency, such as persistent fatigue, weakness, and neurological symptoms like numbness, tingling, or memory problems

The animal data suggest lean mass is preserved, but human body composition data is lacking

Cui Y, Yang D, Wang W, Zhang L, Liu H, Ma S, Guo W, Yao M, Zhang K, Li W (2020) Nicotinamide N-methyltransferase decreases 5-fluorouracil sensitivity in human esophageal squamous cell carcinoma through metabolic reprogramming and promoting the Warburg effect

A diet rich in animal products, fortified foods, nutritional yeast, and supplements helps maintain adequate B12 levels

Blood Sugar Safety: A common concern with metabolic treatments is how they affect insulin

(Neelakantan et al., 2018) observed that systemic administration of NNMTi to mice with diet-induced obesity markedly attenuated WAT mass and body weight, diminished adipocyte volume, and reduced plasma TC levels