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Liver functions and disease symptoms The liver performs many functions, such as aiding digestion (especially fats), synthesizing proteins and hormones, metabolizing and eliminating toxic and waste products, and regulating the immune system
In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion
Parkinson's disease: Mechanisms and models
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With age, mitochondria undergo a progressive deterioration, manifesting as changes in mitochondrial morphology, abundance, and OXPHOS activity 3,4
Cell Stem Cell 31 , 11011112 (2024)
