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Prusiner, S

Patients with this type of bile acid diarrhea have significantly lower FGF19 and higher 7a-hydroxy-4-cholesten-3-one (C4) levels than healthy controls (169), which supports the hypothesis that excess synthesis of bile acids may overflow the reabsorption capacity in the ileum and hence allow bile acids to enter the colon in larger quantities

Journal of Experimental Botany 66, 29132921

For cognitive disorder research, look for trials of FDA-track compounds in registered databases

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