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Future research directions should include: optimizing combination therapies (Mai et al., 2025)

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110 Cardiovascular disturbances, chronic heart failure, pulmonary hypertension, and arrhythmias appear as a particular point of counteraction, much like the disturbances after hypokalemia and hyperkalemia, 41 - 45 and potassium-cell membrane dysfunction or complex muscle disorders produced by potassium 43 - 45 or magnesium overload, 111 or pupil paralysis with atropine