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doi: 10.1111/adb.12975 213

*Correspondence: Jing Yao, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Methods Materials Diamide, dithiothreitol (DTT), ethylenediaminetetraacetic acid (EDTA), GSH, GSSG, and yeast GR were from Sigma-Aldrich, l-cysteine was from Carl Roth, isopropyl--d-1-thiogalactopyranoside was from Serva, methyl ether poly(ethylene glycol) 24 maleimide (mmPEG) was from Iris Biotech, and NADPH was from Gerbu