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This allows the body to get rid of them
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration

29 (1), 145149 (1988) Kumar, M.S., Koteiche, H.A., Claxton, D.P., McHaourab, H.S.: Disulfide cross-links in the interaction of a cataract-linked alphaA-crystallin mutant with betaB1-crystallin

Thus, quenching of excess ROS is very necessary to counter their deleterious effects

In contrast, MRG15S appears to be necessary for maintaining cell proliferation, as its knockout leads to cellular senescence
