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Of fundamental importance, Akagawa and coworkers [18,19] have reported that PQQ serves a functional role in mammalian dehydrogenases such as lactate dehydrogenase (LDH)

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The SPR running buffer was the following: 1 mM HEPES, 150 mM NaCl, 0.05 % TWEEN, 1 mM GSH, 1% DMSO

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