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(2014) developed a refined graded nerve injury and von Frey assessment approach to quantify sex differences in mechanical allodynia, revealing exaggerated and hormone-dependent tactile hypersensitivity in female rats across estrous phases (Nicotra et al., 2014)

Wei et al., in their meta-analysis, concluded that silymarin seems to be safe and well tolerated by patients and, in combination with antiviral drug or protection liver drugs, serum transaminases were reduced [298]

Improving sleep quality leads to better mental health: a meta-analysis of randomised controlled trials

This conclusion requires validation in future studies with a larger sample size

In human embryonic kidney 293 (HEK293) cells, BHB has been shown to induce the acetylation of histone H3 at lysine 9 (H3K9ac) and lysine 14 (H3K14ac) in a dose-dependent manner, resulting in an upregulation of mRNA expression for forkhead transcription factor 3a (FOXO3a) and metallothionein 2 (Mt2) to 1.8 and 1.5 times their baseline levels, respectively

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