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Biochemical production of unlabelled and labelled lipid II, although still a tedious process, becomes feasible in high yield, mainly thanks to the accessibility of high amounts of the limiting undecaprenyl phosphate moiety, which can be isolated from plant leaves 23

Ottawa Heart Institute

It is also possible that de novo synthesized Und-PP undergoes a flip-flop mechanism of dephosphorylation in which Und-PP is first flipped towards the outside side of the membrane, dephosphorylated, and then flipped back to the cytoplasmic side of the membrane for utilization in polysaccharide biogenesis pathways

[DOI] [PubMed] [Google Scholar] 6.Kudo N., Barr A.J., Barr R.L., Desai S., Lopaschuk G.D

Enhanced thromboxane receptor-mediated responses and impaired endothelium-dependent relaxation in human corpus cavernosum from diabetic impotent men: role of protein kinase C activity

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