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A lack of vitamin B12 can lead to neurological disorders such as agitation, hallucinations, changes in natural reflexes, poor muscle function, memory problems, loss of taste, and in severe cases, can cause psychiatric disorders

They are strictly not intended for veterinary or human use

This is largely because our stomachs tend to produce less acid as we get older

Conditions include alcoholic liver disease, viral hepatitis, cirrhosis, and primary or metastatic liver cancer Renal dysfunction : Impaired kidney function reduces B12 elimination, causing accumulation even with normal intake Haematological conditions : Myeloproliferative neoplasms, chronic myeloid leukaemia, polycythaemia vera, and hypereosinophilic syndrome increase transcobalamin production, elevating total serum B12 Laboratory interference : Macro-B12 (immunoglobulin-bound B12) and assay interference can cause spuriously elevated results without true excess In clinical practice, unexplained hypercobalaminaemia should prompt investigation for underlying disease, particularly in patients without obvious supplementation history

A microplate well is coated with an anti-TSH antibody, and TSH-containing samples, standards, and controls are added

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