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MASLD is increasingly recognized as a sex-dimorphic condition: during reproductive age, females generally show lower prevalence and/or severity than males, whereas risk of advanced fibrosis can rise after menopause, suggesting a protective role for estrogens and sex-dependent metabolic and immune regulation (35)

Serum uromodulin is associated with impaired glucose metabolism

The meta-analysis provides compelling evidence supporting the potential of L-carnitine as a natural supplement for enhancing lipid profiles and promoting cardiovascular health